Brain site-specific proteome changes in aging-related dementia

• Main Authors: Manavalan, Arulmani, Mishra, Manisha, Feng, Lin, Sze, Siu Kwan, Akatsu, Hiroyasu, Heese, Klaus
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2014
• Subjects: DRNTU::Science::Biological sciences::Molecular biology
• Online Access: https://hdl.handle.net/10356/106286; http://hdl.handle.net/10220/23994
• Institution: Nanyang Technological University

This study is aimed at gaining insights into the brain site-specific proteomic senescence signature while comparing physiologically aged brains with aging-related dementia brains (for example, Alzheimer’s disease (AD)). Our study of proteomic differences within the hippocampus (Hp), parietal cortex...