Repair of osteochondral defects with rehydrated freeze-dried oligo[poly(ethylene glycol) fumarate] hydrogels seeded with bone marrow mesenchymal stem cells in a porcine model

• Main Authors: Lim, Chin Tat, Ren, Xiafei, Afizah, Mohd Hassan, Tarigan-Panjaitan, Sari, Yang, Zheng, Wu, Yingnan, Chian, Kerm Sin, Mikos, Antonios G., Hui, James Hoi Po
• Other Authors: School of Mechanical and Aerospace Engineering
• Format: Article
• Language: English
• Published: 2014
• Subjects: DRNTU::Science::Medicine::Tissue engineering
• Online Access: https://hdl.handle.net/10356/106292; http://hdl.handle.net/10220/23987
• Institution: Nanyang Technological University

Current surgical techniques for osteochondral injuries in young active patients are inadequate clinically. Novel strategies in tissue engineering are continuously explored in this area. Despite numerous animal studies that have shown encouraging results, very few large-scale clinical trials have bee...