Structure, sequence and ion-exchange of left-handed G-quadruplexes

• المؤلف الرئيسي: Bakalar, Blaz
• مؤلفون آخرون: Phan Anh Tuan
• التنسيق: Theses and Dissertations
• اللغة: English
• منشور في: 2019
• الموضوعات: DRNTU::Science::Biological sciences::Biophysics
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/106467; http://hdl.handle.net/10220/47993
• المؤسسة: Nanyang Technological University

Besides the canonical double-stranded helical B-DNA structure, DNA can form four-stranded G-quadruplex structures composed of stacked guanine G-tetrads. Until the recent first example of a left-handed structure named Z-G4, all solved G-quadruplex structures adopted a right-handed helical fold. We...