Expression, purification, crystallization and preliminary X-ray analysis of full-length human RIG-I

The human innate immune system can detect invasion by microbial pathogens through pattern-recognition receptors that recognize structurally conserved pathogen-associated molecular patterns. Retinoic acid-inducible gene I (RIG-I)-like helicases (RLHs) are one of the two major families of pattern-reco...

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Bibliographic Details
Main Authors: Kwok, Jane, Hui, Kenrie P. Y., Lescar, Julien, Kotaka, Masayo
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2015
Subjects:
Online Access:https://hdl.handle.net/10356/106637
http://hdl.handle.net/10220/25042
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Institution: Nanyang Technological University
Language: English