Correlation between membrane partitioning and functional activity in a single lipid vesicle assay establishes design guidelines for antiviral peptides

Correlation between membrane partitioning and functional activity in a single lipid vesicle assay establishes design guidelines for antiviral peptides

The nanometer-scale discrimination of virus-rupturing peptides is tested using lipid membrane platforms. In combination with single-vesicle analysis of peptide-induced vesicle rupture, a correlation between membrane partitioning and biologically relevant activities is established. Taken together, th...

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Bibliographic Details
Main Authors: Jackman, Joshua A., Saravanan, Rathi, Zhang, Yibang, Tabaei, Seyed R., Cho, Nam-Joon
Other Authors: School of Chemical and Biomedical Engineering
Format: Article
Language:English
Published: 2015
Subjects:
DRNTU::Science::Medicine::Biomedical engineering
Online Access:https://hdl.handle.net/10356/106839
http://hdl.handle.net/10220/25155
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/106839
http://hdl.handle.net/10220/25155

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