Correlation between membrane partitioning and functional activity in a single lipid vesicle assay establishes design guidelines for antiviral peptides
The nanometer-scale discrimination of virus-rupturing peptides is tested using lipid membrane platforms. In combination with single-vesicle analysis of peptide-induced vesicle rupture, a correlation between membrane partitioning and biologically relevant activities is established. Taken together, th...
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Main Authors: | Jackman, Joshua A., Saravanan, Rathi, Zhang, Yibang, Tabaei, Seyed R., Cho, Nam-Joon |
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Other Authors: | School of Chemical and Biomedical Engineering |
Format: | Article |
Language: | English |
Published: |
2015
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/106839 http://hdl.handle.net/10220/25155 |
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Institution: | Nanyang Technological University |
Language: | English |
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