Angiopoietin-like 4 increases pulmonary tissue leakiness and damage during influenza pneumonia

• Main Authors: Chow, Vincent Tak Kwong, Tan, Nguan Soon, Seet, Ju Ee, Choi, Hyung Won, Buist, Martin Lindsay, Li, Liang, Chong, Han Chung, Ng, Say Yong, Kwok, Ka Wai, Teo, Ziqiang, Tan, Eddie Han Pin, Choo, Chee Chong
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2015
• Subjects: DRNTU::Science::Biological sciences
• Online Access: https://hdl.handle.net/10356/107002; http://hdl.handle.net/10220/25239
• Institution: Nanyang Technological University

Excessive host inflammatory responses negatively impact disease outcomes in respiratory infection. Host-pathogen interactions during the infective phase of influenza are well studied, but little is known about the host’s response during the repair stage. Here, we show that influenza infection stimul...