Intracellular reduction-responsive sheddable copolymer micelles for targeted anticancer drug delivery

• Main Authors: Zhao, Yanli, Zhang, Yuanyuan, Qu, Qiuyu, Li, Menghuan
• Other Authors: School of Materials Science & Engineering
• Format: Article
• Language: English
• Published: 2015
• Subjects: DRNTU::Science::Chemistry::Organic chemistry
• Online Access: https://hdl.handle.net/10356/107074; http://hdl.handle.net/10220/25270
• Institution: Nanyang Technological University

Intracellular, reduction-responsive, amphiphilic, copolymer micelles with cancer cell specificity were developed. The copolymer was prepared with controlled molecular weight and functionalities using a double-headed initiator consisting of a disulfide linkage and folic acid targeting unit. The polym...