PANI : an interactive data-driven tool for target prioritization in signaling networks

• Main Authors: Bhowmick, Sourav S., Chua, Huey-Eng, Tucker-Kellogg, Lisa, Wang, Yingqi, Dewey Jr., C. Forbes, Yu, Hanry
• Other Authors: School of Computer Engineering
• Format: Conference or Workshop Item
• Language: English
• Published: 2013
• Subjects: DRNTU::Engineering::Computer science and engineering::Computer applications::Life and medical sciences
• Online Access: https://hdl.handle.net/10356/107227; http://hdl.handle.net/10220/16672
• Institution: Nanyang Technological University

Biological network analysis often aims at the target identification problem, which is to predict which molecule to inhibit (or activate) for a disease treatment to achieve optimum efficacy and safety. A related goal, arising from the increasing availability of high-throughput screening (HTS), is to...