A structural and functional study on Cot (MAPKKK8)
Cot (cancer Osaka thyroid, also known as Tpl-2), a proto-oncogenic kinase, is a member of the MAPKKK family and plays a key role in the regulation of the immune response to pro-inflammatory stimuli such as LPS (lipopolysaccharide) and TNF- (tumor necrosis factor-). After LPS-stimulation, Cot activ...
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Format: | Theses and Dissertations |
Language: | English |
Published: |
2008
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Online Access: | https://hdl.handle.net/10356/13576 |
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Institution: | Nanyang Technological University |
Language: | English |