Inhibiting S100B(ββ) for activating wild-type p53 : design of stapled peptides

S100B(ββ) is a member of the S100B protein family and is distributed in a cell-specific manner. Its levels are elevated in several cancers such as malignant melanoma and correlate directly with poor prognosis in patients. S100B(ββ) directly interacts with the tumor suppressor p53, inhibiting tetrame...

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Bibliographic Details
Main Authors: Kannan, Srinivasaraghavan, Aronica, Pietro G. A., Tan, Yaw Sing, Verma, Chandra Shekhar
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2020
Subjects:
Online Access:https://hdl.handle.net/10356/137422
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Institution: Nanyang Technological University
Language: English