Carbene-catalyzed formal [3+3] cycloaddition reaction for access to substituted 2-phenylbenzothiazoles

• Main Authors: Ni, Zhibin, Mou, Chengli, Zhu, Xun, Qi, Puying, Yang, Song, Chi, Robin Yonggui, Jin, Zhichao
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2020
• Subjects: Science::Chemistry::Organic chemistry; 2-Phenylbenzothiazoles; N-Heterocyclic Carbene
• Online Access: https://hdl.handle.net/10356/137897
• Institution: Nanyang Technological University

A carbene-catalyzed oxidative cycloaddition reaction is developed for efficient access to multi-functionalized 2-phenylbenzothiazoles. A broad scope of heavily substituted arenes bearing 2-benzothiazole groups have been prepared in good to excellent yields. The remote C(sp2)–H bond in the substitute...