Synergistic lysosomal activatable polymeric nanoprobe encapsulating pH sensitive imidazole derivative for tumor diagnosis

• Main Authors: Chen, Xiaohong, Chen, Ziwen, Hu, Benhui, Cai, Pingqiang, Wang, Sa, Xiao, Shuzhang, Wu, Yun-Long, Chen, Xiaodong
• Other Authors: School of Materials Science & Engineering
• Format: Article
• Language: English
• Published: 2020
• Subjects: Engineering::Materials; Lysosome; PH Sensitive
• Online Access: https://hdl.handle.net/10356/138943
• Institution: Nanyang Technological University

Developing optical tumor imaging probes with minimal background noise is very important for its early detection of small lesions and accurate diagnosis of cancer. To overcome the bottleneck of low signal to noise ratio and sensitivity, it needs further improvement in fluorescent probe design and und...