Incorporation of calcium sulfate dihydrate into hydroxyapatite microspheres to improve the release of bone morphogenetic protein-2 and accelerate bone regeneration

• Main Authors: Baek, Jaeuk, Lee, Hyun, Jang, Tae-Sik, Song, Juha, Kim, Hyoun-Ee, Jung, Hyun-Do
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2020
• Subjects: Engineering::Chemical engineering; Hydroxyapatite Microspheres; Bone Morphogenetic Protein
• Online Access: https://hdl.handle.net/10356/139281
• Institution: Nanyang Technological University

In this study, hydroxyapatite (HA)-based microspheres with the ability to deliver bone morphogenetic protein-2 (BMP-2) were developed for accelerating bone regeneration. The incorporation of calcium sulfate dihydrate (CSD) in the HA matrix improved the rate of BMP-2 release from the microspheres. Un...