Mode of heparin attachment to nanocrystalline hydroxyapatite affects its interaction with bone morphogenetic protein-2

Heparin has a high affinity for bone morphogenetic protein-2 (BMP-2), which is a key growth factor in bone regeneration. The aim of this study was to investigate how the rate of release of BMP-2 was affected when adsorbed to nanosized hydroxyapatite (HAP) particles functionalized with heparin by dif...

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Bibliographic Details
Main Authors: Goonasekera, Chandhi S., Jack, Kevin S., Bhakta, Gajadhar, Rai, Bina, Luong-Van, Emma, Nurcombe, Victor, Cool, Simon M., Cooper-White, Justin J., Grøndahl, Lisbeth
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Article
Language:English
Published: 2018
Subjects:
Online Access:https://hdl.handle.net/10356/89942
http://hdl.handle.net/10220/46465
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Institution: Nanyang Technological University
Language: English