Simultaneous binding of hybrid molecules constructed with dual DNA-binding components to a G-quadruplex and its proximal duplex

Simultaneous binding of hybrid molecules constructed with dual DNA-binding components to a G-quadruplex and its proximal duplex

A G-quadruplex (quadruplex) is a nucleic acid secondary structure adopted by guanine-rich sequences and is considered to be relevant to various pharmacological and biological contexts. Although a number of researchers have endeavored to discover and develop quadruplex-interactive molecules, poor lig...

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Bibliographic Details
Main Authors: Asamitsu, Sefan, Obata, Shunsuke, Phan, Anh Tuân, Hashiya, Kaori, Bando, Toshikazu, Sugiyama, Hiroshi
Other Authors: School of Physical and Mathematical Sciences
Format: Article
Language:English
Published: 2020
Subjects:
Science::Biological sciences
Dual DNA-binding Components
G-quadruplexes
Online Access:https://hdl.handle.net/10356/139379
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/139379

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