Tetrad-binding ligands do not bind specifically to left-handed G-quadruplexes
G-quadruplexes (G4s) are attractive anticancer targets. While right-handed G4s have been extensively investigated with many specific ligands reported, left-handed G4s formed by natural DNA have been recently discovered. Here we show that ligands specific for right-handed G4s, such as Phen-DC3 and RH...
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| Main Authors: | , |
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| 格式: | Article |
| 語言: | English |
| 出版: |
2023
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| 在線閱讀: | https://hdl.handle.net/10356/164741 |
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| 機構: | Nanyang Technological University |
| 語言: | English |