A funneled conformational landscape governs flavivirus fusion peptide interaction with lipid membranes
During host cell infection by flaviviruses such as dengue and Zika, acidic pH within the endosome triggers a conformational change in the envelope protein on the outer surface of the virion. This results in exposure of the ∼15 residue fusion peptide (FP) region, freeing it to induce fusion between t...
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Main Authors: | Marzinek, Jan Kazimierz, Bag, Nirmalya, Huber, Roland G., Holdbrook, Daniel A., Wohland, Thorsten, Verma, Chandra Shekhar, Bond, Peter John |
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Other Authors: | School of Biological Sciences |
Format: | Article |
Language: | English |
Published: |
2020
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/139524 |
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Institution: | Nanyang Technological University |
Language: | English |
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