Nanomechanically visualizing drug-cell interaction at the early stage of chemotherapy

• Main Authors: Wu, Yun-Long, Engl, Wilfried, Hu, Benhui, Cai, Pingqiang, Leow, Wan Ru, Tan, Nguan Soon, Lim, Chwee Teck, Chen, Xiaodong
• Other Authors: School of Materials Science & Engineering
• Format: Article
• Language: English
• Published: 2020
• Subjects: Engineering::Materials; Nanomechanics; Cell Traction Force
• Online Access: https://hdl.handle.net/10356/140202
• Institution: Nanyang Technological University

A detailed understanding of chemotherapy is determined by the response of cell to the formation of the drug-target complex and its corresponding sudden or eventual cell death. However, visualization of this early but important process, encompassing the fast dynamics as well as complex network of mol...