Chromatin topology defines cell identity and phenotypic transition in human cancer and fungal pathogen

Higher-order chromatin organization plays an important role in epigenetic regulation of gene expression. Chromatin topology has been increasingly recognized to define cellular identity. Alterations in chromatin conformation are often associated with phenotypic changes and can even lead to cellular s...

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Bibliographic Details
Main Author: Chen, Yao
Other Authors: Amartya Sanyal
Format: Thesis-Doctor of Philosophy
Language:English
Published: Nanyang Technological University 2020
Subjects:
Online Access:https://hdl.handle.net/10356/140893
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Institution: Nanyang Technological University
Language: English