Polycystic kidney disease : new knowledge and future promises

• Main Authors: Foo, Jia Nee, Xia, Yun
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2020
• Subjects: Science::Medicine; Kidney Dysfunction; Developmental Biology
• Online Access: https://hdl.handle.net/10356/141155
• Institution: Nanyang Technological University

Polycystic kidney disease (PKD) is one of the most common genetic kidney diseases, characterized by the formation of fluid-filled renal cysts, which eventually lead to end-stage renal disease. Despite several decades of investigation, explicit molecular and cellular mechanisms underpinning renal cys...