Synthesis of the proposed structure of afzeliindanone

• Main Authors: Rita, Mohamed Husaini Abdul Rahman, Chong, Sherilyn Shi Min, Bates, Roderick Wayland
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2020
• Subjects: Science::Chemistry; Alkynes; Cyclotrimerization
• Online Access: https://hdl.handle.net/10356/141249
• Institution: Nanyang Technological University

A synthesis of the proposed structure of afzeliindanone was achieved by using an alkyne [2+2+2]-cyclotrimerization as a key step. The data for the synthetic material were found not to match those for the natural material, indicating a structural misassignment.