Divergent ring-opening coupling between cyclopropanols and alkynes under cobalt catalysis

• Main Authors: Yang, Junfeng, Shen, Yixiao, Lim, Yang Jie, Yoshikai, Naohiko
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2018
• Subjects: Cyclopropanols; Alkynes; DRNTU::Science::Chemistry::Biochemistry
• Online Access: https://hdl.handle.net/10356/89453; http://hdl.handle.net/10220/46255
• Institution: Nanyang Technological University

Cobalt–diphosphine catalysts promote ring-opening coupling reactions between cyclopropanols and unactivated internal alkynes, affording either β-alkenyl ketones or multisubstituted cyclopentenol derivatives in good yields with good to excellent regioselectivities. The chemoselectivity between these...