Large 3‐Mb deletions at 22q11.2 locus in Parkinson's disease and schizophrenia

• Main Authors: Foo, Jia Nee, Lee, Jimmy, Tan, Louis C., Liu, Jianjun, Tan, Eng-King
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2020
• Subjects: Science::Biological sciences::Genetics; Parkinson's Disease; Genetics
• Online Access: https://hdl.handle.net/10356/141341
• Institution: Nanyang Technological University

22q11.2 microdeletions are among the most common deletions found in humans. Whereas most cases present in early childhood, a large fraction remain undetected into adulthood. Adult carriers are at increased risk of developing schizophrenia.1 More recently, these deletions have also been associated wi...