Amorphous nanoparticle complex of perphenazine and dextran sulfate as a new solubility enhancement strategy of antipsychotic perphenazine

Objective: The objective of this study is to develop a new solubility enhancement strategy of anti- psychotic drug – perphenazine (PPZ) – in the form of its amorphous nanoparticle complex (or nanoplex) with polyelectrolyte dextran sulfate (DXT). Significance: Poor bioavailability of PPZ necessitated...

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Main Authors: Dong, Bingxue, Hadinoto, Kunn
其他作者: School of Chemical and Biomedical Engineering
格式: Article
語言:English
出版: 2020
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在線閱讀:https://hdl.handle.net/10356/141825
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機構: Nanyang Technological University
語言: English