Amorphous nanoparticle complex of perphenazine and dextran sulfate as a new solubility enhancement strategy of antipsychotic perphenazine
Objective: The objective of this study is to develop a new solubility enhancement strategy of anti- psychotic drug – perphenazine (PPZ) – in the form of its amorphous nanoparticle complex (or nanoplex) with polyelectrolyte dextran sulfate (DXT). Significance: Poor bioavailability of PPZ necessitated...
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Main Authors: | , |
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格式: | Article |
語言: | English |
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2020
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在線閱讀: | https://hdl.handle.net/10356/141825 |
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機構: | Nanyang Technological University |
語言: | English |