Non-viral gene therapy using multifunctional nanoparticles : status, challenges, and opportunities

• Main Authors: Lin, Guimiao, Li, Li, Panwar, Nishtha, Wang, Jie, Tjin, Swee Chuan, Wang, Xiaomei, Yong, Ken-Tye
• Other Authors: School of Electrical and Electronic Engineering
• Format: Article
• Language: English
• Published: 2020
• Subjects: Engineering::Electrical and electronic engineering
• Online Access: https://hdl.handle.net/10356/141958
• Institution: Nanyang Technological University

Gene delivery for molecular-level therapeutics is regarded as a prospective remedial route to cure human diseases by the medical community. The major challenge for delivering genes in vivo is the lack of suitable delivery vehicles possessing high transfection efficiencies and low cytotoxicity. Curre...