Biodegradable polymer-coated multifunctional graphene quantum dots for light-triggered synergetic therapy of pancreatic cancer

• Main Authors: Yang, Chengbin, Chan, Kok Ken, Xu, Gaixia, Yin, Ming-jie, Lin, Guimiao, Wang, Xiaomei, Lin, Wei-Jen, Muhammad Danang Birowosuto, Zeng, Shuwen, Ogi, Takashi, Okuyama, Kikuo, Permatasari, Fitri Aulia, Iskandar, Ferry, Chen, Chih-Kuang, Yong, Ken-Tye
• Other Authors: School of Electrical and Electronic Engineering
• Format: Article
• Language: English
• Published: 2021
• Subjects: Engineering::Electrical and electronic engineering; Graphene Quantum Dots; Biodegradable Charged Polyester Vector
• Online Access: https://hdl.handle.net/10356/151241
• Institution: Nanyang Technological University

In this work, we reported the synthesis of an engineered novel nanocarrier composed of biodegradable charged polyester vectors (BCPVs) and graphene quantum dots (GQDs) for pancreatic cancer (MiaPaCa-2 cells) therapy applications. Such a nanocarrier was utilized to co-load doxorubicin (DOX) and small...