Non-viral gene therapy using multifunctional nanoparticles : status, challenges, and opportunities

• المؤلفون الرئيسيون: Lin, Guimiao, Li, Li, Panwar, Nishtha, Wang, Jie, Tjin, Swee Chuan, Wang, Xiaomei, Yong, Ken-Tye
• مؤلفون آخرون: School of Electrical and Electronic Engineering
• التنسيق: مقال
• اللغة: English
• منشور في: 2020
• الموضوعات: Engineering::Electrical and electronic engineering
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/141958
• المؤسسة: Nanyang Technological University

Gene delivery for molecular-level therapeutics is regarded as a prospective remedial route to cure human diseases by the medical community. The major challenge for delivering genes in vivo is the lack of suitable delivery vehicles possessing high transfection efficiencies and low cytotoxicity. Curre...