The molecular functions of hepatocyte nuclear factors - in and beyond the liver

• Main Authors: Lau, Hwee Hui, Ng, Natasha Hui Jin, Loo, Larry Sai Weng, Joanita Jasmen, Teo, Adrian Kee Keong
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2020
• Subjects: Science::Medicine; Hepatocyte Nuclear Factor; Liver
• Online Access: https://hdl.handle.net/10356/142126
• Institution: Nanyang Technological University

The hepatocyte nuclear factors (HNFs) namely HNF1α/β, FOXA1/2/3, HNF4α/γ and ONECUT1/2 are expressed in a variety of tissues and organs, including the liver, pancreas and kidney. The spatial and temporal manner of HNF expression regulates embryonic development and subsequently the development of mul...