Metformin from mother to unborn child – are there unwarranted effects?

by Nguyen, Linh, Chan, Shiao-Yng, Teo, Adrian Kee Keong
Published 2018

Cellular stress drives pancreatic plasticity

by Valdez, Ivan Achel, Teo, Adrian Kee Keong, Kulkarni, Rohit N.
Published 2016

Dissecting diabetes/metabolic disease mechanisms using pluripotent stem cells and genome editing tools

by Teo, Adrian Kee Keong, Gupta, Manoj K., Doria, Alessandro, Kulkarni, Rohit N.
Published 2015

Knowledge gaps in rodent pancreas biology : taking human pluripotent stem cell-derived pancreatic beta cells into our own hands

by Santosa, Munirah Mohamad, Low, Blaise Su Jun, Pek, Nicole Min Qian, Teo, Adrian Kee Keong
Published 2018

The molecular functions of hepatocyte nuclear factors - in and beyond the liver

by Lau, Hwee Hui, Ng, Natasha Hui Jin, Loo, Larry Sai Weng, Joanita Jasmen, Teo, Adrian Kee Keong
Published 2020

Proinflammatory cytokines induce endocrine differentiation in pancreatic ductal cells via STAT3-dependent NGN3 activation

by Valdez, Ivan Achel, Dirice, Ercument, Gupta, Manoj K., Shirakawa, Jun, Teo, Adrian Kee Keong, Kulkarni, Rohit N.
Published 2018

New insights into human beta cell biology using human pluripotent stem cells

by Amirruddin, Nur Shabrina, Low, Blaise Su Jun, Lee, Kok Onn, Tai, E Shyong, Teo, Adrian Kee Keong
Published 2021

Early developmental perturbations in a human stem cell model of MODY5/HNF1B pancreatic hypoplasia

by Teo, Adrian Kee Keong, Lau, Hwee Hui, Valdez, Ivan Achel, Dirice, Ercument, Tjora, Erling, Raeder, Helge, Kulkarni, Rohit N.
Published 2018

Charting the next century of insulin replacement with cell and gene therapies

by Lau, Hwee Hui, Gan, Shu Uin, Lickert, Heiko, Shapiro, Andrew Mark James, Lee, Kok Onn, Teo, Adrian Kee Keong
Published 2021

HNF1A binds and regulates the expression of SLC51B to facilitate the uptake of estrone sulfate in human renal proximal tubule epithelial cells

by Chan, Jun Wei, Neo, Claire Wen Ying, Ghosh, Soumita, Choi, Hyungwon, Lim, Su Chi, Tai, E Shyong, Teo, Adrian Kee Keong
Published 2023

FGFR-mediated ERK1/2 signaling contributes to mesendoderm and definitive endoderm formation in vitro

by Lau, Hwee Hui, Amirruddin, Nur Shabrina, Loo, Larry Sai Weng, Chan, Jun Wei, Iich, Elhadi, Krishnan, Vidhya Gomathi, Hoon, Shawn, Teo, Adrian Kee Keong
Published 2023

Progressive endoplasmic reticulum stress over time due to human insulin gene mutation contributes to pancreatic beta cell dysfunction

by Amirruddin, Nur Shabrina, Tan, Wei Xuan, Tan, Yaw Sing, DAPHNE SU-LYN GARDNER, YONG MONG BEE, CHANDRA SHEKHAR VERMA, Hoon, Shawn, Lee, K.O., Teo, Adrian Kee Keong
Published 2021

HNF4A haploinsufficiency in MODY1 abrogates liver and pancreas differentiation from patient-derived induced pluripotent stem cells

by Joanita Jasmen, Ng, Natasha Hui Jin, Lim, Chang Siang, Lau, Hwee Hui, Krishnan, Vidhya Gomathi, Kadiwala, Juned, Kulkarni, Rohit N., Ræder, Helge, Vallier, Ludovic, Hoon, Shawn, Teo, Adrian Kee Keong
Published 2019

Defective insulin receptor signaling in hPSCs skews pluripotency and negatively perturbs neural differentiation

by Teo, Adrian Kee Keong, Linh Nguyen, Gupta, Manoj K., Lau, Hwee Hui, Loo, Larry Sai Weng, Jackson, Nicholas, Lim, Chang Siang, Mallard, William, Gritsenko, Marina A., inn, J.L., Smith, Richard D., Qian, Wei-Jun, Kulkarni, Rohit N.
Published 2022

Decreased GLUT2 and glucose uptake contribute to insulin secretion defects in MODY3/HNF1A hiPSC-derived mutant ? cells

by Low, Blaise Su Jun, Lim, Chang Siang, Ding, Shirley Suet Lee, Tan, Yaw Sing, Ng, Natasha Hui Jin, Krishnan, Vidhya Gomathi, Ang, Su Fen, Neo, Claire Wen Ying, Verma, Chandra S., Hoon, Shawn, Lim, Su Chi, Tai, E. Shyong, Teo, Adrian Kee Keong
Published 2022

PAX4 loss of function increases diabetes risk by altering human pancreatic endocrine cell development

by Lau, Hwee Hui, Krentz, Nicole A. J., Abaitua, Fernando, Perez-Alcantara, Marta, Chan, Jun-Wei, Ajeian, Jila, Ghosh, Soumita, Lee, Yunkyeong, Yang, Jing, Thaman, Swaraj, Champon, Benoite, Sun, Han, Jha, Alokkumar, Hoon, Shawn, Tan, Nguan Soon, Gardner, Daphne Su-Lyn, Kao, Shih Ling, Tai, E Shyong, Gloyn, Anna L., Teo, Adrian Kee Keong
Published 2024

Trans-interaction of risk loci 6p24.1 and 10q11.21 is associated with endothelial damage in coronary artery disease

by Tay, Kai Yi, Wu, Kan Xing, Chioh, Florence Wen Jing, Autio, Matias Ilmari, Pek, Nicole Min Qian, Narmada, Balakrishnan Chakrapani, Tan, Sock-Hwee, Low, Adrian Fatt-Hoe, Lian, Michelle Mulan, Chew, Elaine Guo Yan, Lau, Hwee Hui, Kao, Shih Ling, Teo, Adrian Kee Keong, Foo, Jia Nee, Foo, Roger Sik Yin, Heng, Chew Kiat, Chan, Mark Yan Yee, Cheung, Christine
Published 2023