Metformin from mother to unborn child – are there unwarranted effects?

بواسطة Nguyen, Linh, Chan, Shiao-Yng, Teo, Adrian Kee Keong
منشور في 2018

Cellular stress drives pancreatic plasticity

بواسطة Valdez, Ivan Achel, Teo, Adrian Kee Keong, Kulkarni, Rohit N.
منشور في 2016

Dissecting diabetes/metabolic disease mechanisms using pluripotent stem cells and genome editing tools

بواسطة Teo, Adrian Kee Keong, Gupta, Manoj K., Doria, Alessandro, Kulkarni, Rohit N.
منشور في 2015

Knowledge gaps in rodent pancreas biology : taking human pluripotent stem cell-derived pancreatic beta cells into our own hands

بواسطة Santosa, Munirah Mohamad, Low, Blaise Su Jun, Pek, Nicole Min Qian, Teo, Adrian Kee Keong
منشور في 2018

The molecular functions of hepatocyte nuclear factors - in and beyond the liver

بواسطة Lau, Hwee Hui, Ng, Natasha Hui Jin, Loo, Larry Sai Weng, Joanita Jasmen, Teo, Adrian Kee Keong
منشور في 2020

Proinflammatory cytokines induce endocrine differentiation in pancreatic ductal cells via STAT3-dependent NGN3 activation

بواسطة Valdez, Ivan Achel, Dirice, Ercument, Gupta, Manoj K., Shirakawa, Jun, Teo, Adrian Kee Keong, Kulkarni, Rohit N.
منشور في 2018

New insights into human beta cell biology using human pluripotent stem cells

بواسطة Amirruddin, Nur Shabrina, Low, Blaise Su Jun, Lee, Kok Onn, Tai, E Shyong, Teo, Adrian Kee Keong
منشور في 2021

Early developmental perturbations in a human stem cell model of MODY5/HNF1B pancreatic hypoplasia

بواسطة Teo, Adrian Kee Keong, Lau, Hwee Hui, Valdez, Ivan Achel, Dirice, Ercument, Tjora, Erling, Raeder, Helge, Kulkarni, Rohit N.
منشور في 2018

Charting the next century of insulin replacement with cell and gene therapies

بواسطة Lau, Hwee Hui, Gan, Shu Uin, Lickert, Heiko, Shapiro, Andrew Mark James, Lee, Kok Onn, Teo, Adrian Kee Keong
منشور في 2021

HNF1A binds and regulates the expression of SLC51B to facilitate the uptake of estrone sulfate in human renal proximal tubule epithelial cells

بواسطة Chan, Jun Wei, Neo, Claire Wen Ying, Ghosh, Soumita, Choi, Hyungwon, Lim, Su Chi, Tai, E Shyong, Teo, Adrian Kee Keong
منشور في 2023

FGFR-mediated ERK1/2 signaling contributes to mesendoderm and definitive endoderm formation in vitro

بواسطة Lau, Hwee Hui, Amirruddin, Nur Shabrina, Loo, Larry Sai Weng, Chan, Jun Wei, Iich, Elhadi, Krishnan, Vidhya Gomathi, Hoon, Shawn, Teo, Adrian Kee Keong
منشور في 2023

Progressive endoplasmic reticulum stress over time due to human insulin gene mutation contributes to pancreatic beta cell dysfunction

بواسطة Amirruddin, Nur Shabrina, Tan, Wei Xuan, Tan, Yaw Sing, DAPHNE SU-LYN GARDNER, YONG MONG BEE, CHANDRA SHEKHAR VERMA, Hoon, Shawn, Lee, K.O., Teo, Adrian Kee Keong
منشور في 2021

HNF4A haploinsufficiency in MODY1 abrogates liver and pancreas differentiation from patient-derived induced pluripotent stem cells

بواسطة Joanita Jasmen, Ng, Natasha Hui Jin, Lim, Chang Siang, Lau, Hwee Hui, Krishnan, Vidhya Gomathi, Kadiwala, Juned, Kulkarni, Rohit N., Ræder, Helge, Vallier, Ludovic, Hoon, Shawn, Teo, Adrian Kee Keong
منشور في 2019

Defective insulin receptor signaling in hPSCs skews pluripotency and negatively perturbs neural differentiation

بواسطة Teo, Adrian Kee Keong, Linh Nguyen, Gupta, Manoj K., Lau, Hwee Hui, Loo, Larry Sai Weng, Jackson, Nicholas, Lim, Chang Siang, Mallard, William, Gritsenko, Marina A., inn, J.L., Smith, Richard D., Qian, Wei-Jun, Kulkarni, Rohit N.
منشور في 2022

Decreased GLUT2 and glucose uptake contribute to insulin secretion defects in MODY3/HNF1A hiPSC-derived mutant ? cells

بواسطة Low, Blaise Su Jun, Lim, Chang Siang, Ding, Shirley Suet Lee, Tan, Yaw Sing, Ng, Natasha Hui Jin, Krishnan, Vidhya Gomathi, Ang, Su Fen, Neo, Claire Wen Ying, Verma, Chandra S., Hoon, Shawn, Lim, Su Chi, Tai, E. Shyong, Teo, Adrian Kee Keong
منشور في 2022

PAX4 loss of function increases diabetes risk by altering human pancreatic endocrine cell development

بواسطة Lau, Hwee Hui, Krentz, Nicole A. J., Abaitua, Fernando, Perez-Alcantara, Marta, Chan, Jun-Wei, Ajeian, Jila, Ghosh, Soumita, Lee, Yunkyeong, Yang, Jing, Thaman, Swaraj, Champon, Benoite, Sun, Han, Jha, Alokkumar, Hoon, Shawn, Tan, Nguan Soon, Gardner, Daphne Su-Lyn, Kao, Shih Ling, Tai, E Shyong, Gloyn, Anna L., Teo, Adrian Kee Keong
منشور في 2024

Trans-interaction of risk loci 6p24.1 and 10q11.21 is associated with endothelial damage in coronary artery disease

بواسطة Tay, Kai Yi, Wu, Kan Xing, Chioh, Florence Wen Jing, Autio, Matias Ilmari, Pek, Nicole Min Qian, Narmada, Balakrishnan Chakrapani, Tan, Sock-Hwee, Low, Adrian Fatt-Hoe, Lian, Michelle Mulan, Chew, Elaine Guo Yan, Lau, Hwee Hui, Kao, Shih Ling, Teo, Adrian Kee Keong, Foo, Jia Nee, Foo, Roger Sik Yin, Heng, Chew Kiat, Chan, Mark Yan Yee, Cheung, Christine
منشور في 2023