Molecular insights into evolution, mutations and receptor-binding specificity of influenza A and B viruses from outpatients and hospitalized patients in Singapore

• Main Authors: Ivan, Fransiskus Xaverius, Zhou, Xinrui, Lau, Suk Hiang, Rashid, Shamima, Teo, Jasmine S. M., Lee, Hong Kai, Koay, Evelyn S., Chan, Kwai Peng, Leo, Yee Sin, Chen, Mark I. Cheng, Kwoh, Chee Keong, Chow, Vincent T.
• Other Authors: School of Computer Science and Engineering
• Format: Article
• Language: English
• Published: 2020
• Subjects: Engineering::Computer science and engineering; Influenza; A/H1N1 viruses
• Online Access: https://hdl.handle.net/10356/142170
• Institution: Nanyang Technological University

Background: This study compared the genomes of influenza viruses that caused mild infections among outpatients and severe infections among hospitalized patients in Singapore, and characterized their molecular evolution and receptor-binding specificity. Methods: The complete genomes of influenza A/H1...