Switch and trace : recombinase genetics in zebrafish

• Main Authors: Carney, Tom J., Mosimann, Christian
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2020
• Subjects: Science::Medicine; Transgenesis; Zebrafish Genome
• Online Access: https://hdl.handle.net/10356/142180
• Institution: Nanyang Technological University

Transgenic approaches are instrumental for labeling and manipulating cells and cellular machineries in vivo. Transgenes have traditionally been static entities that remained unaltered following genome integration, limiting their versatility. The development of DNA recombinase-based methods to modify...