Conservative site-specific and single-copy transgenesis in human LINE-1 elements

Conservative site-specific and single-copy transgenesis in human LINE-1 elements

Genome engineering of human cells plays an important role in biotechnology and molecular medicine. In particular, insertions of functional multi-transgene cassettes into suitable endogenous sequences will lead to novel applications. Although several tools have been exploited in this context, safety...

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Bibliographic Details
Main Authors: Vijaya Chandra, Shree Harsha, Makhija, Harshyaa, Peter, Sabrina, Myint Wai, Cho Mar, Li, Jinming, Zhu, Jindong, Ren, Zhonglu, D'Alcontres, Martina Stagno, Siau, Jia Wei, Chee, Sharon, Ghadessy, Farid John, Dröge, Peter
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2018
Subjects:
Human Genome
Single Copy Transgenesis
DRNTU::Science::Biological sciences
Online Access:https://hdl.handle.net/10356/88523
http://hdl.handle.net/10220/45846
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/88523
http://hdl.handle.net/10220/45846

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