A versatile genomic transgenesis platform with enhanced λ integrase for human Expi293F cells

A versatile genomic transgenesis platform with enhanced λ integrase for human Expi293F cells

Reliable cell-based platforms to test and/or produce biologics in a sustainable manner are important for the biotech industry. Utilizing enhanced λ integrase, a sequence-specific DNA recombinase, we developed a novel transgenesis platform involving a fully characterized single genomic locus as an ar...

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Bibliographic Details
Main Authors: Siddiqui, Asim Azhar, Peter, Sabrina, Ngoh, Eve Zi Xian, Wang, Cheng-I, Ng, Shirelle, Dangerfield, John A., Gunzburg, Walter H., Dröge, Peter, Makhija, Harshyaa
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2023
Subjects:
Science
Human Cell Line Engineering
λ Integrase
Expi293F Cells
Biotherapeutics
Site-Specific Transgenesis
Microencapsulation
Online Access:https://hdl.handle.net/10356/168601
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/168601

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