A YajQ-LysR-like, cyclic di-GMP-dependent system regulating biosynthesis of an antifungal antibiotic in a crop-protecting bacterium, Lysobacter enzymogenes

• Main Authors: Han, Sen, Shen, Danyu, Wang, Yu-Chuan, Chou, Shan-Ho, Gomelsky, Mark, Gao, Yong-Gui, Qian, Guoliang
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2020
• Subjects: Science::Biological sciences; Antifungal Antibiotic; CdgL
• Online Access: https://hdl.handle.net/10356/142259
• Institution: Nanyang Technological University

YajQ, a binding protein of the universal bacterial second messenger cyclic di-GMP (c-di-GMP), affects virulence in several bacterial pathogens, including Xanthomonas campestris. In this bacterium, YajQ interacts with the transcription factor LysR. Upon c-di-GMP binding, the whole c-di-GMP-YajQ-LysR...