Dynamics of BCL-2 family of proteins in early pancreatic progenitors and β-cells

BCL-2 family proteins play an important role in the regulation of cell survival and death. However, there are also certain members that exhibit tissue- and developmental stage-specific expression and function. Here, I report a unique reciprocal relationship between BCL-xL (not BCL2) and BAK during e...

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Bibliographic Details
Main Author: Loo, Larry Sai Weng
Other Authors: Francesc Xavier Roca Castella
Format: Thesis-Doctor of Philosophy
Language:English
Published: Nanyang Technological University 2020
Subjects:
Online Access:https://hdl.handle.net/10356/142359
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Institution: Nanyang Technological University
Language: English