Dynamics of BCL-2 family of proteins in early pancreatic progenitors and β-cells

• المؤلف الرئيسي: Loo, Larry Sai Weng
• مؤلفون آخرون: Francesc Xavier Roca Castella
• التنسيق: Thesis-Doctor of Philosophy
• اللغة: English
• منشور في: Nanyang Technological University 2020
• الموضوعات: Science::Biological sciences
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/142359
• المؤسسة: Nanyang Technological University

BCL-2 family proteins play an important role in the regulation of cell survival and death. However, there are also certain members that exhibit tissue- and developmental stage-specific expression and function. Here, I report a unique reciprocal relationship between BCL-xL (not BCL2) and BAK during e...