Structural plasticity of BCL-2 family proteins and its functional implication in apoptosis

Dysregulated apoptosis has been implicated in the development of several diseases including cancer and neurodegenerative diseases. Bcl-2 family proteins regulate mitochondrial apoptosis through homo- and hetero-dimerization between pro- and anti-apoptotic Bcl-2 proteins. The first part of this stu...

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Bibliographic Details
Main Author: Choi, Minjoo
Other Authors: Yoon Ho Sup
Format: Theses and Dissertations
Language:English
Published: 2018
Subjects:
Online Access:http://hdl.handle.net/10356/73522
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Institution: Nanyang Technological University
Language: English