Recognition of nucleosomes by protein factors that regulate chromatin structure and dynamics

One of the key players in genomic structure and dynamics is chromatin modification enzymes, which regulate epigenetic marks and alter chromatin activity. The first part of this thesis is focused on poly(ADP-ribose) polymerase 1 (PARP1) and sirtuin-6 (SIRT6), two chromatin modification enzymes that m...

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Bibliographic Details
Main Author: Lee, Phoi Leng
Other Authors: Curtis Alexander Davey
Format: Thesis-Doctor of Philosophy
Language:English
Published: Nanyang Technological University 2020
Subjects:
Online Access:https://hdl.handle.net/10356/142395
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Institution: Nanyang Technological University
Language: English