Recognition of the nucleosome by the chromatin remodeler atrx
The α-thalassemia mental retardation X-linked protein (ATRX) is an ATP-dependent chromatin remodeler. Congenital mutations in ATRX cause a rare inherited disease called ATRX syndrome and somatic mutations in ATRX may involve in cancer development. There are two main domains in ATRX. One is the C-ter...
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| Format: | Theses and Dissertations |
| Language: | English |
| Published: |
2017
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| Online Access: | http://hdl.handle.net/10356/69606 |
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| Institution: | Nanyang Technological University |
| Language: | English |