Recognition of the nucleosome by the chromatin remodeler atrx

• المؤلف الرئيسي: Feng, Xiaoyu
• مؤلفون آخرون: Daniela Rhodes
• التنسيق: Theses and Dissertations
• اللغة: English
• منشور في: 2017
• الموضوعات: DRNTU::Science::Biological sciences
• الوصول للمادة أونلاين: http://hdl.handle.net/10356/69606
• المؤسسة: Nanyang Technological University

The α-thalassemia mental retardation X-linked protein (ATRX) is an ATP-dependent chromatin remodeler. Congenital mutations in ATRX cause a rare inherited disease called ATRX syndrome and somatic mutations in ATRX may involve in cancer development. There are two main domains in ATRX. One is the C-ter...