The optical effective attenuation coefficient as an informative measure of brain health in aging

• Main Authors: Chiarelli, Antonio M., Low, Kathy A., Maclin, Edward L., Fletcher, Mark A., Kong, Tania S., Zimmerman, Benjamin, Tan, Chin Hong, Sutton, Bradley P., Fabiani, Monica, Gratton, Gabriele
• Other Authors: School of Social Sciences
• Format: Article
• Language: English
• Published: 2020
• Subjects: Social sciences::Psychology; Diffuse Optical Imaging (DOI); Effective Attenuation Coefficient (EAC)
• Online Access: https://hdl.handle.net/10356/142467
• Institution: Nanyang Technological University

Aging is accompanied by widespread changes in brain tissue. Here, we hypothesized that head tissue opacity to near-infrared light provides information about the health status of the brain’s cortical mantle. In diffusive media such as the head, opacity is quantified through the Effective Attenuation...