A novel, five-marker alternative to CD16-CD14 gating to identify the three human monocyte subsets

• المؤلفون الرئيسيون: Ong, Siew-Min, Teng, Karen, Newell, Evan, Chen, Hao, Chen, Jinmiao, Loy, Thomas, Yeo, Tsin-Wen, Fink, Katja, Wong, Siew Cheng
• مؤلفون آخرون: School of Biological Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2020
• الموضوعات: Science::Biological sciences; Monocyte Subsets; CD16
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/142475
• المؤسسة: Nanyang Technological University

Human primary monocytes are heterogeneous in terms of phenotype and function, but are sub-divided only based on CD16 and CD14 expression. CD16 expression distinguishes a subset of monocytes with highly pro-inflammatory properties from non-CD16 expressing "classical" monocytes. CD14 express...