The mutator phenotype : adapting microbial evolution to cancer biology

The mutator phenotype hypothesis was postulated almost 40 years ago to reconcile the observation that while cancer cells display widespread mutational burden, acquisition of mutations in non-transformed cells is a rare event. Moreover, it also suggested that cancer evolution could be fostered by inc...

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Main Authors: Natali, Federica, Rancati, Giulia
其他作者: School of Biological Sciences
格式: Article
語言:English
出版: 2020
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在線閱讀:https://hdl.handle.net/10356/142479
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機構: Nanyang Technological University
語言: English