Stapling a G-quadruplex specific peptide

Stapling a G-quadruplex specific peptide

G-quadruplex (G4) is a non-canonical four-stranded nucleic acid structure and the RHAU helicase has been identified to have high specificity for recognition of parallel-stranded G4s. We have designed and synthesized two stapled peptide analogues of the G4-specfic motif of RHAU, which preserve the G4...

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Bibliographic Details
Main Authors: Yaneva, Militsa Yavorova, Cheong, Vee Vee, Cheng, Jun Kee, Lim, Kah Wai, Phan, Anh Tuân
Other Authors: School of Physical and Mathematical Sciences
Format: Article
Language:English
Published: 2020
Subjects:
Science::Biological sciences
Science::Chemistry
G-quadruplex
G-quadruplex-binding Protein
Online Access:https://hdl.handle.net/10356/143224
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/143224

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