Modeling Parkinson’s disease in yeast

• Main Author: Neo, Natalie Ling Yin
• Other Authors: Choe Young Jun
• Format: Final Year Project
• Language: English
• Published: Nanyang Technological University 2020
• Subjects: Science::Biological sciences
• Online Access: https://hdl.handle.net/10356/143292
• Institution: Nanyang Technological University

Alpha-Synuclein (α-Syn) is a protein mostly found in the presynaptic terminal of neurons in the brain. It is implicated in the neuropathology of Parkinson’s Disease (PD) to form Lewy bodies when accumulated progressively. Previous studies have shown that wild-type and 6 mutant α-Syn forms amyloid fi...