Identification of genetic modifiers of Parkinson’s disease in yeast

Alpha-synuclein (α-Syn) is a critical pathogenic player of Parkinson's disease (PD), which accumulates in the form of Lewy Bodies (LBs). It was previously reported that LBs resulted from protein-rich amyloidogenic fibrils. However, multiple studies in recent years report that they are instead a...

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Bibliographic Details
Main Author: Yap, Ernest Gim Seng
Other Authors: Choe Young Jun
Format: Final Year Project
Language:English
Published: Nanyang Technological University 2023
Subjects:
Online Access:https://hdl.handle.net/10356/172188
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Institution: Nanyang Technological University
Language: English