Dissolving triamcinolone-embedded microneedles for the treatment of keloids : a single-blinded intra-individual controlled clinical trial

• Main Authors: Tan, Colin W. X., Tan, Wei Ding, Srivastava, Ruchir, Yow, Ai Ping, Wong, Damon Wing Kee, Tey, Hong Liang
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2020
• Subjects: Science::Medicine; Keloids; Microneedles
• Online Access: https://hdl.handle.net/10356/143367
• Institution: Nanyang Technological University

Keloids are a prevalent chronic skin disorder with significant psychosocial morbidity. Intralesional corticosteroid injections are the first-line treatment but are painful and require repeated injections by medical professionals. Dissolving microneedles are a novel method of cutaneous drug delivery that induces minimal/no pain and can be self-administered. The objective of the study was to evaluate the efficacy and safety of triamcinolone-embedded dissolving microneedles in treatment of keloids.