AIE featured inorganic-organic Core@Shell nanoparticles for high-efficiency siRNA delivery and real-time monitoring

• Main Authors: He, Xuewen, Yin, Feng, Wang, Dongyuan, Xiong, Ling-Hong, Kwok, Ryan T. K., Gao, Peng Fei, Zhao, Zheng, Lam, Jacky W. Y., Yong, Ken-Tye, Li, Zigang, Tang, Ben Zhong
• Other Authors: School of Electrical and Electronic Engineering
• Format: Article
• Language: English
• Published: 2020
• Subjects: Engineering::Electrical and electronic engineering; Aggregation-induced Emission; Nanocarrier
• Online Access: https://hdl.handle.net/10356/143658
• Institution: Nanyang Technological University

RNA interference (RNAi) is demonstrated as one of the most powerful technologies for sequence-specific suppression of genes in disease therapeutics. Exploration of novel vehicles for small interfering RNA (siRNA) delivery with high efficiency, low cytotoxicity, and self-monitoring functionality is p...