Optical spectroscopic ultrasound displacement imaging : a feasibility study

• Main Authors: Duan, Tingyang, Lan, Hengrong, Zhong, Hongtao, Zhou, Meng, Zhang, Ruochong, Gao, Fei
• Other Authors: School of Electrical and Electronic Engineering
• Format: Article
• Language: English
• Published: 2020
• Subjects: Engineering::Electrical and electronic engineering; Optical Spectroscopic Characterization; Photoacoustic Imaging
• Online Access: https://hdl.handle.net/10356/143881
• Institution: Nanyang Technological University

Photoacoustic imaging has been intensively studied in recent years and many of the achievements have already been applied in clinical diagnosis and therapy, e.g., using spectroscopic photoacoustic imaging to extract functional and molecular information. However, spectroscopic photoacoustic imaging requires expensive and bulky tunable laser source, which severely hinders its further development toward a portable device. In this paper, we propose a novel imaging method, named optical spectroscopic ultrasound displacement (OSUD) imaging, which enables optical spectroscopic imaging in deep scattering tissue using multiple low-cost continuous-wave laser sources and ultrasound imaging equipment. The principle of the OSUD imaging method will be introduced, followed by preliminary experimental results. The OSUD imaging may exploit the deep penetration merit of ultrasound and provide another pathway to provide spectroscopic optical absorption contrast in deep scattering tissue beyond commonly used photoacoustic imaging, which will be further validated in the future work.