Rapid, sensitive and highly specific label-free fluorescence biosensor for microRNA by branched rolling circle amplification

• Main Authors: Ma, Qian, Li, Pin, Gao, Zhiqiang, Li, Sam Fong Yau
• 其他作者: Lee Kong Chian School of Medicine (LKCMedicine)
• 格式: Article
• 語言: English
• 出版: 2020
• 主題: Science::Medicine; MicroRNA; Terpyridine Zinc
• 在線閱讀: https://hdl.handle.net/10356/144341
• 機構: Nanyang Technological University

A simple fluorescence biosensor for rapid and sensitive target microRNA (miRNA) quantification by branched rolling circle amplification (BRCA) is developed in this work. Target miRNA functions as primer to recognize and hybridize with a circle DNA template, initiating rolling circle amplification (R...